smartgene - 17-8-2016 at 07:06
If you react acetophenone and hypochlorous acid what are the products you get. would you get phenylacyl chloride or some other product
PHILOU Zrealone - 17-8-2016 at 07:20
With HOCl you would get C6H5-CO-CH2-Cl and side products depending on your initial réactants.
With NaOCl you would get C6H5-CO2Na and HCCl3.
smartgene - 17-8-2016 at 08:41
Is there any way to better the yields with minimum side products
PHILOU Zrealone - 17-8-2016 at 09:12
And by the way haloacetophenone are highly lacrymatory!
byko3y - 17-8-2016 at 18:20
In neutral conditions acetophenone is mostly in ketone form, thus no bromination occurs in neutral conditions or the rate of bromination is extremely
small. This way 1-phenylalcohol can be cleanly oxidized into acetophenone with HOCl, which is a well established procedure.