glassplass - 16-3-2016 at 13:37
What would happen with triprolidine molecule under "birch reduction condition"?
I need answer from experts,at least expirienced chemists...
Thanks.
chemrox - 17-3-2016 at 18:28
Shooting from the hip: It would reduce the toluene group to a methyl cyclohexadiene. The pyridine group would be left as it is. I think.. depends on
the amount of Li. More base further reduction..
MeshPL - 19-3-2016 at 09:23
That double bond conjugated with aromatic ring may also be reduced. Pyridine ring is reducable by sodium in alcohol, so it MAY be reduced in condition
of birch reduction, but I wouldn't be certain whether or not and to what extent and if it's reduction would be favoured over reduction of benzene
ring.