Sciencemadness Discussion Board

amide decomposition

rannyfash - 28-2-2012 at 12:07

is there a way to maintain peptide linkage in a protein at high temperatures without it decomposing, would it be as simple as an anhydrous environment to prevent hydrolysis?

GreenD - 28-2-2012 at 12:44

Proteins also denature at high temperatures into irreversible conformations - is that not going to be a problem?

rannyfash - 29-2-2012 at 16:29

its really just the acid chain, not really bothered about 'r' groups reacting