cosmo - 18-9-2011 at 15:11
What do you guys think of this overall synthetic scheme?
Possible?
The main thing I'm uncertain about is whether or not the cyanate group will behave the same way as a carbonitrile during reaction with the Grignard
reagent.
I believe that this method would avoid dehydration to the corresponding N-substituted 4-phenyl-1,2,3,6-tetrahydropyridine. It would of course be
ill-advised to attempt to synth this compound at all, since it would be highly illegal to do so; just wondering about the validity of the chemistry in
this.