Khusimol
Names | |
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IUPAC name
[(1R,2S,5S,8R)-7,7-dimethyl-6-methylidene-2-tricyclo[6.2.1.01,5]undecanyl]methanol
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Other names
Khusenol
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Properties | |
C15H24O | |
Molar mass | 220.356 g/mol |
Appearance | Oily liquid |
Density | 0.974 g/cm2[1] |
Boiling point | 150 °C (302 °F; 423 K) (at 0.02 mmHg)[2] |
Immiscible | |
Solubility | Soluble with organic solvents |
Vapor pressure | ~o mmHg |
Hazards | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
Infobox references | |
Khusimol is a sesquiterpene found in the essential oil of vetiver (Chrysopogon zizanioides). It contains a tricyclic hydrocarbon core, with a hydroxy methyl group, two methyl groups and a methylene group. It constitutes the biggest part of oil of vetiver, around 15%.
Contents
Properties
Chemical
As it contains a primary alcohol, khusimol can be oxidized with the Jones reagent to its respective carboxylic acid.
Physical
Khusimol is an oily liquid, immiscible with water, bus soluble in organic solvents.
Availability
Khusimol can be extracted from the essential oil of vetiver plant. Methanol is often used as the choice solvent. The essential oil contains around 15% khusimol by weight.[3][4]
Preparation
It's better to extract it and purify it from the essential oil of vetiver plant.
Projects
- Compound collecting
- Make esters
- Make anti-fungal agent
- Treat acne and sores
Handling
Safety
There is little data available about khusimol's toxicity.
Storage
Should be kept in closed airtight bottles, away from air an light.
Disposal
No special disposal is required. Can be diluted with water and poured down the drain.
References
- ↑ Nigam; Radecka; Komae; Journal of Pharmaceutical Sciences; vol. 57; nb. 6; (1968); p. 1029 - 1030
- ↑ Takahashi,S.; Chemical and pharmaceutical bulletin; vol. 16; (1968); p. 2447 - 2450
- ↑ https://www.sciencedirect.com/science/article/abs/pii/S0040403901997047?via%3Dihub
- ↑ https://pubs.acs.org/doi/abs/10.1021/np50112a001