Omer
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Registered: 12-3-2016
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Help with mannich and lacton
Hello everyone...
Iam willing to perform mannich rxn with starting material contain a lacton ring...
Using dimethyl amine and formaldehyde with ethanol as solvent
But im wondering... Is it will be possible to obtain product with out using acidic media...
Actually I tried but it failed
failed(I donT know why)is it due to acid absence
And what about lacton ring after ope ING...theoretically it will recycle agin.. Right!?
Actually I dont need to lose other strating material as it took me alot of effords to obtain...
Help pls
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MeshPL
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You want to attatch that dimethylamine and formaldehyde in alpha position next to lactone carbonyl or next to some other carbonyl, it would be helpful
if you named the substrate.
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Nicodem
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Thread Moved
12-3-2016 at 08:39 |
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