Vorel
Harmless
Posts: 2
Registered: 24-11-2012
Location: USA
Member Is Offline
Mood: No Mood
|
|
GVS-111 analogs
I am interested in learning more about the pharmacological mechanisms of action behind substance GVS-111
I would appreciate it if someone could point me to literature that would help me potentially explore analogs of this substance in the future and how
to safely and effectively test them for activity and toxicity.
I am an undergraduate biology major (USA) and I am open to thoughts and ideas as well as suggestions as to how I should approach my studies to align
myself more closely with researchers that study such things.
Thanks!
|
|
|
chemrox
International Hazard
Posts: 2961
Registered: 18-1-2007
Location: UTM
Member Is Offline
Mood: LaGrangian
|
|
Have you found a good source for it? Anyway google gvs-111 and you will get the wiki as well as quite a few other articles. It seems to be
neuroprotective nootropic compound similar to piracetam. It would probably be a good thing to take with mdma. If I were a student again I'd
probably load up on it. If I could afford it that is. I found the patent.
Oh and welcome aboard!
Attachment: US5439930.gsv-111.Noopt.pdf (698kB)
This file has been downloaded 654 times
[Edited on 25-11-2012 by chemrox]
"When you let the dumbasses vote you end up with populism followed by autocracy and getting back is a bitch." Plato (sort of)
|
|
|
Satan
Hazard to Others
Posts: 126
Registered: 1-5-2009
Member Is Offline
Mood: No Mood
|
|
Noopept is very cheap (50 USD dollars for 1000 doses). I remember that only one analog was stronger, it was ethyl ester of
N-(phenylacetyl)-L-prolylalanine.
More info:
http://www.scirus.com/srsapp/search?q=GVS-111
|
|
|
chemrox
International Hazard
Posts: 2961
Registered: 18-1-2007
Location: UTM
Member Is Offline
Mood: LaGrangian
|
|
| Quote: | | Noopept is very cheap (50 USD dollars for 1000 doses). |
any idea how many doses/day for ultimate brain fitness?
"When you let the dumbasses vote you end up with populism followed by autocracy and getting back is a bitch." Plato (sort of)
|
|
|
Vorel
Harmless
Posts: 2
Registered: 24-11-2012
Location: USA
Member Is Offline
Mood: No Mood
|
|
Quote: Originally posted by chemrox  | | Quote: | | Noopept is very cheap (50 USD dollars for 1000 doses). |
any idea how many doses/day for ultimate brain fitness? |
The literature varies but I get good results from 100 mg p.o. b.i.d.
Tests on rabbits in 2002 demonstrated no permanent physiological changes after being fed either 10 mg/kg 100 mg/kg for 6 months.
But I digress...
I would like to keep this discussion strictly restricted to the pharmacological activity of GVS-111 so it doesn't get cluttered up with posts about
"how much should I take lol"
For that stuff I suggest you read through this thread
http://www.bluelight.ru/vb/threads/611375-The-Big-amp-Dandy-...
I want to know more about how the structure of Noopept influences its pharmacological activity.
I would appreciate it if someone could point me to literature or anything useful that describes how the electronics of the various moieties present
influence the activity of noopept.
This may eventually result in a computational / molecular receptor binding study.
I want to know the hard facts behind what we know about this compound.
|
|
|
Satan
Hazard to Others
Posts: 126
Registered: 1-5-2009
Member Is Offline
Mood: No Mood
|
|
From my experiments I can say that 100mg is far too much for an adult man - I work with authentic and pure noopept. 10-30mg is normal dosage range,
above 50mg + caffeine you get to feel like everybody around is lazy and stupid 
dosages this high also dulls some of emotional responses.
|
|
|
![[*]](images/xpblue/default_icon.gif){kind=icon}
