Sciencemadness Discussion Board

where to obtain high boiling point ketone for decarboxylation

Neo-6 - 19-10-2010 at 05:33

any ideas, i have asked local pharmacist for cyclohexaone but the had no.
how have you gotten decarboxylations done, is there suppliers that ship internationally?

jon - 19-10-2010 at 05:46

your going to have to be a little more resourceful than that.
does'nt this belong in the aquisition forum?

Methansaeuretier - 19-10-2010 at 06:36

Turpentine with spearmint oil does work very well and is OTC

90%+ Yield of crude material from tryptophane (extracted with 5% AcOH and precipitated with aq. NaOH).

70-80% of pure material after destillation.


In some forums I read that DMF (also OTC in some countries) does work nearly quantitative without any catalysts, but workup sucks.

[Edited on 19-10-2010 by Methansaeuretier]

madscientist - 19-10-2010 at 16:23

Caraway oil works as well. It and spearmint oil are enantiomers (carvone).

Have you considered camphor? Cheap and easy enough to find.

zed - 20-10-2010 at 16:36

Acetophenone is considered excellent for such work.

Assuming that this material can be formed in good yield by the pyrolysis of Pb or Fe--acetate and Benzoic Acid. Why not use these cheap, readily available materials to make yourself a liter or so of acetophenone?



[Edited on 21-10-2010 by zed]