Orotic acid
From Sciencemadness Wiki
| Names | |
|---|---|
| IUPAC name
1,2,3,6-Tetrahydro-2,6-dioxo-4-pyrimidinecarboxylic acid
| |
| Other names
2,4-dioxo-1H-pyrimidine-6-carboxylic acid
6-Carboxy-2,4-dihydroxypyrimidine 6-Carboxyuracil Uracil-6-carboxylic acid | |
| Properties | |
| C5H4N2O4 | |
| Molar mass | 156.097 g/mol |
| Appearance | White solid |
| Odor | Odorless |
| Melting point | 345.5 °C (653.9 °F; 618.6 K) (decomposition) |
| Boiling point | Decomposes |
| 0.182 g/100 ml (20 °C) | |
| Solubility | Reacts with bases |
| Vapor pressure | ~0 mmHg |
| Acidity (pKa) | pKa1 = 2.07 pKa2 = 9.45 |
| Hazards | |
| Safety data sheet | Sigma-Aldrich |
| Lethal dose or concentration (LD, LC): | |
| LD50 (Median dose)
|
2,000 mg/kg (mouse, oral) |
| Related compounds | |
| Related compounds
|
Sodium orotate |
| Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Orotic acid is an organic chemical compound, a pyrimidinedione and a carboxylic acid.
Contents
Properties
Chemical
Orotic acid reacts with bases to form their respective salts.
Physical
Orotic acid is a solid compound, poorly soluble in water.
Availability
Orotic acid is sold by chemical suppliers.
Orotic acid can be found in certain plants, like Lotus uliginosus or Lotus filicaulis.
Preparation
Can be prepared by acidifying magnesium orotate, which is available as mineral supplement.
Projects
- Make orotate salts
Handling
Safety
Orotic acid has low toxicity, though it may be irritant.
Storage
In closed airtight bottles, away from bases and oxidizers.
Disposal
Orotic acid and its salts have poor water solubility and don't pose a threat for the environment. They can be diluted and poured down the drain.
