tr41414
Hazard to Self
Posts: 56
Registered: 14-9-2006
Location: EU
Member Is Offline
Mood: No Mood
|
|
Phenyl alkyl ketone synthesis
Does anyone have any reference to synthesis of 3,4,5-trimethoxyphenyl amyl ketone?
Probably the simplest of reactants would be hexanoic acid and the substituted benzoic acid... Will the methoxy groups survive the harsh reaction
conditions?
Here are some industrial preps. of propiophenone, which is similar (phenyl ethyl ketone)... sounds like a tube furnace reaction to me...
http://www.freepatentsonline.com/4950763.html
http://www.freepatentsonline.com/4172097.html
Is it posible to do a pirolysis reaction (Pb, Ca or Zn salt of mixed acids) or a reaction with the anhydride of the acid (or is that possible only
with acetic anhydrise)?
|
|
|
Organikum
resurrected
Posts: 2339
Registered: 12-10-2002
Location: Europe
Member Is Offline
Mood: frustrated
|
|
It should work if you run it under massive reduced pressure with a flow of hot inert gas. Look for lead(II)salts.
[Edited on 24-5-2007 by Organikum]
|
|
|
![[*]](images/xpblue/default_icon.gif){kind=icon}
