benzoyl
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Product of tert-butanesulfinyl ketimines
If you take a tert-butanesulfinyl ketimine, reduce it with NaBH4 and then cleave the suflinyl group via hydroylsis, is a primary or secondary amine
produced?
The original Ellman paper suggests a primary amine, but other sources indicate that tert-butanesulfinyl ketimines produce secondary amines and
tert-butanesulfinyl aldimines produce primary amines.
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Sigmatropic
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Ketimine --> primary amine with secondary carbon
Aldimine --> primary amine with primary carbon
see attached scheme.
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gdflp
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Thread Moved
22-9-2017 at 08:18 |
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