LiD
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Which is the thermodynamically more stable product?
I had done a reaction recently:
Here, I used Wacker conditions, so PdCl2, CuCl2 as an oxidant and ethyene glycol as an alcohol. The reaction went perfectly, the only problem was that
I got mixed products, both product 1 and 2.
I would like to ask that if I would heat up the reaction and slow down the addition of the reagents, than would it be possible to get only product 1
or only product 2?
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kch
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I believe the first product is formed because it is symmetric. Not sure.
[Edited on 8-18-2013 by kch]
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Dany
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Hello LiD,
if you know the structure of your products this mean you have done the NMR spectrum. You can also use your crude NMR spectrum to guess the ratio of
each product. if the first molecule is present in bigger quantity, you can say that the first molecule is more stable from the second one. Generally
speaking, it is difficult to guess stability from the structure. DFT (Density Dunctional Theory) or other reliable theoretical model, should be used
to calculate the energy of each molecule, based on this you can be more confident when you judge.
Dany.
[Edited on 18-8-2013 by Dany]
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