Isomerization of Perrottetinene
I was hoping someone here could comment on the possibility of converting perrottetinene between the cis and trans isomers. It has been proposed that
using aluminum chloride you could convert from the natural form, with its weaker affinity at CB1, to the unnatural form with what I believe will be 2x
greater affinity (based on SAR). It should have affinity rivaling the most common cannabinoid but with higher efficacy, perhaps yielding a medical
useful cannabinoid.
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