Nexuswalker
Harmless
Posts: 4
Registered: 29-9-2011
Member Is Offline
Mood: No Mood
|
|
Hordenine Extraction
Hey all,
I'm new here and couldn't find any rules for posting on here, anyway I am looking to extract Hordenine from Cacti. This is a phenethylamine compound
and I'm wondering what would be the best way to extract it.
My thoughts are an acid base extraction should work, however my chemistry knowledge is limited at the moment as I've just started my degree so any
thoughts are appreciated.
|
|
|
fledarmus
Hazard to Others
Posts: 187
Registered: 23-6-2011
Member Is Offline
Mood: No Mood
|
|
A quick search of Google Scholar for "hordenine isolation" gives this reference first among a host of others:
Cactus alkaloids X: Isolation of hordenine and N-methyltyramine from ariocarpus kotschoubeyanus
[Edited on 29-9-2011 by fledarmus]
|
|
|
simba
Hazard to Others
Posts: 175
Registered: 20-5-2011
Member Is Offline
Mood: No Mood
|
|
A/B extraction should work.
|
|
|
Nicodem
Super Moderator
Posts: 4230
Registered: 28-12-2004
Member Is Offline
Mood: No Mood
|
|
An unwritten rule for this forum section is to always provide all the necessary references when opening a new thread. Members that formulate questions
in an unanswerable form, or who are either unable or unwilling to provide references, should only open threads in the Beginnings section so that the
repliers answer with more patience and provide a more comprehensive answer.
| Quote: | | I am looking to extract Hordenine from Cacti. This is a phenethylamine compound and I'm wondering what would be the best way to extract it.
|
It should be obvious to you that it is not possible to answer that question without knowing what do you wish to extract it from. Without knowing the
approximate content and the content of other compounds with similar chemical properties, any reply is futile. For any meaningful answer you need to
first provide a minimum necessary information, which is the exact taxonomical data of the species involved so that a literature search for the
isolation procedure can be looked for.
Not just any acid-base based extraction, given that hordenine is both a weak base and a weak acid (it is amphoteric)! In any case, that would not
separate it from other compounds with similar properties.
…there is a human touch of the cultist “believer” in every theorist that he must struggle against as being
unworthy of the scientist. Some of the greatest men of science have publicly repudiated a theory which earlier they hotly defended. In this lies their
scientific temper, not in the scientific defense of the theory. - Weston La Barre (Ghost Dance, 1972)
Read the The ScienceMadness Guidelines!
|
|
|
Nicodem
|
Thread Moved
1-10-2011 at 01:52 |
Nexuswalker
Harmless
Posts: 4
Registered: 29-9-2011
Member Is Offline
Mood: No Mood
|
|
Hey sorry I thought this thread was deleted, cheers for the info, now I know!
I am looking to extract this from a selenicereus grandiflorus (moonlight cacti), this species contains Tyramine, N-methyltyramine, and
N-N-DimethylTyramine (Hordenine).
How would I go about finding out which acid/base extraction to use to pull the crude alkaloids out if one (or more) are amphoteric? Is this a case of
just researching?
Thanks all
|
|
|
Nexuswalker
Harmless
Posts: 4
Registered: 29-9-2011
Member Is Offline
Mood: No Mood
|
|
If anyone else is interested I can post up the above said paper detailing isolation. I can't understand it all of it yet but maybe someone else can.
The TLC method use for the final isolation does not seem complicated though.
[Edited on 26-10-2011 by Nexuswalker]
|
|
|
Nexuswalker
Harmless
Posts: 4
Registered: 29-9-2011
Member Is Offline
Mood: No Mood
|
|
or not.....
|
|
|
Chemistry Alchemist
Hazard to Others
Posts: 403
Registered: 2-8-2011
Location: Australia
Member Is Offline
Mood: No Mood
|
|
Can post it if u want, help others in advance incase thay would like to try the extraction
|
|
|
![[*]](images/xpblue/default_icon.gif){kind=icon}
