g3ovn
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Registered: 8-11-2010
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Oxidation of 4-nitrotoluene
Source: http://www.lambdasyn.org/synfiles/benzocain.htm
I want the p-aminobenzoic acid, but instead of reducing the p-nitrotoluene to p-toluidine hcl, basification, acetylation and KMnO4, can't i just
oxidize the p-nitrotoluene to p-nitrobenzoic acid first and then just reduce the nitro to p-aminobenzoic hcl?
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Cloner
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Registered: 7-12-2004
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The question is whether you can obtain p-nitrobenzoic acid from p-nitrotoluene with KMnO4. Somehow I think this is going to be trouble, but if you are
willing to try that would be great. The next step should be possible.
See http://en.wikipedia.org/wiki/4-Nitrobenzoic_acid.
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