ItalianChemist
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cholesterol esters
Hi to all!
I've tried the synthesis of cholesteryl benzoate, but I didn't obtained a good result.
I mixed cholesterol and TEA in the right quantities in acetone, then I added a little excess of benzoyl chloride, and I stirred the solution for 30
minutes.
I Buchner filtered the solid, but I don't obtained the product that I wanted.
What can be happened? In which way can I obtain pure cholesteryl benzoate?
Thanks!
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jon
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you should give it more time it takes longer with triethylamine.
wash, rinse, dry, repeat
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ItalianChemist
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Quote: Originally posted by jon  | you should give it more time it takes longer with triethylamine.
wash, rinse, dry, repeat |
Thank you!
I'll stir the solution for more time
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jon
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make sure your acetone is dry also...
actually if memory serves it takes stirring overnight for esterification of those steroid type molecules to complete.
but that is with anhydrides and pyridine.
acid chlorides react faster.
[Edited on 7-7-2011 by jon]
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