SelfStarter
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Cyclohexylamine
Are there any places that sell cyclohexylamine to individuals. Oddly this is the only chem in the last 2 years that I have had problems sourcing
within the last 2 years and I work in my lab almost daily.
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Magic Muzzlet
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Yes there are.
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SelfStarter
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I am sure there are too but I was hoping that someone might point me in the right direction.
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not_important
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Depends on where you live for starters - which country, which region in larger countries.
You might consider making it from cyclohexanone which is easier to find, often being part of the solvents and prepping agents for plastic piping.
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Random
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Quote: Originally posted by not_important  | Depends on where you live for starters - which country, which region in larger countries.
You might consider making it from cyclohexanone which is easier to find, often being part of the solvents and prepping agents for plastic piping.
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How is amine most easily obtained form ketone like cyclohexanone?
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UKnowNotWatUDo
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Form the imine from ammonia and then reduce.
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SelfStarter
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I had also considered forming the oxime and reducing but then I will be wasting more expensive reagents on a cheaper one.
I am in the midwest USA.
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mario840
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Why waste hydroxylamine ?
Cyclohexane + H2SO/HNO3 (nitration) -------> 1-nitrocyclohexane , then reduction to cyclohexylamine with Sn/HCl .
It's so simple
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Lambda-Eyde
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| Quote: Originally posted by mario840 | Why waste hydroxylamine ?
Cyclohexane + H2SO/HNO3 (nitration) -------> 1-nitrocyclohexane , then reduction to cyclohexylamine with Sn/HCl .
It's so simple |
Saturated hydrocarbons are much less reactive towards substitution than aromatic hydrocarbons. I doubt it will work unless you give me a reference for
that reaction.
That being said, I have seen a paper on vapor-phase nitration of alkanes (aliphatic) with conc. nitric acid at high temperatures.
This just in: 95,5 % of the world population lives outside the USA
Please drop by our IRC channel: #sciencemadness @ irc.efnet.org
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DJF90
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Leuckart reaction on cyclohexanone.
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mario840
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Cyclohexane + sodium azide -------> cyclohexyl azide ----->(reduction with Zn/NH4Cl) -----> cyclohexylamine , hight yielding 90% in 10
minutes refluxing !!!!!!!!!!!!!!!!!!!!!
References:
Reduction of Azides to Amines or Amides
With Zinc and Ammonium Chloride as Reducing Agent
http://www.erowid.org/archive/rhodium/chemistry/azide2amine....
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Nicodem
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And where is the reference for this:
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Nicodem
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Thread Split
19-5-2012 at 01:08 |
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