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Author: Subject: Quick question about decarboxylation
mrzwing
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[*] posted on 28-3-2025 at 22:19
Quick question about decarboxylation


I'm looking into the decarboxylation reaction and just wonder if i am on the right track with something that come to mind.
I see some reactions where they create a more acidic environment before heating, is it that the acidic environment gives an access of H+ ions to aid the substitution.
sorry if i use the incorrect terms.
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Osmiridium
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[*] posted on 29-3-2025 at 04:09


Which compound do you want to decarboxylate?

The conditions may vary since some carboxylic acids decarboxylate easily while others do not. But usually heat and dry distillation is involved.
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mrzwing
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[*] posted on 31-3-2025 at 04:53


i'm looking in to ibotenic acid decarboxylation, read a study where the efficiency and amount och decarboxylation of ibotenic acid to muscarine was much higher if the mixture was at a ph lower than 3 if i remember correctly during heating.
and made me think if it was the excess of h+ ions that would help the process.
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