Quieraña
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Off-topic conjecture split from "A foray into phenethylamines of the Shulgin kind"
Did anyone know that there is a triacetoxybenzaldehyde? I wonder what THAT endproduct would be like!
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Tsjerk
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Don't you think that will just hydrolyze into the phenolate?
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Quieraña
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My inexperience doesn't assume this. I'd hate for you to be correct, merely because more variety sounds better. I also stumbled onto
mercaptobenzaldehyde, which may go the 2-CT route, but idk enough at this time due to only reading, dreaming, remembering, and sighing.
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clearly_not_atara
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Phenyl esters are rather unstable. In particular, phenyl ester derivatives of cannabinoids and opioids are known to be deacylated in the body. In this
case, the corresponding hydroxyphenethylamines are known to be rather neurotoxic in some cases, making them undesirable byproducts.
http://en.wikipedia.org/wiki/Oxidopamine
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Quieraña
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All I know is, I hunched that these benzaldehydes existed, so I Google them, and they do. Btw so does methyldioxyephedrine, but I don't know what one
could use that for. I suppose down the road there will be antidepressants that are also antihistamines. Thorazine was being made and sold as an
antihistamine and was found to have other use at different dosages. Cyclobenzaprine also the same thing (a tricyclic antidepressant that in low dosage
is a muscle relaxer). Sorry to veer off subject. If the truacetoxy component stays after the henry reaction, that is after the substance is a
nitrostyrene, perhaps it will keep to its moiety..
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Texium
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Of course they exist. Virtually any compound that doesn't contain any impossible bonds can exist. From all of your posts, Quieraña, it sounds like
you have not made any earnest effort to study and understand organic chemistry, and instead you make conjectures based on patterns you see but don't
understand, combined with pure wishful thinking. I'm splitting this off but leaving the thread open (for now).
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Texium
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Thread Moved
13-12-2023 at 10:34 |
Quieraña
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Texium, pardon me for growing interest in chemistry later on in life. My interests in sciences other than chemistry took the forefront and then I'd
grown interest when I had a chance to look at some college level texts. That said, my apologies for wasting anyone's time. After having looked at a
few things regarding the benzodioxole component it seems you all are correct and the curiosity I've had regarding wondering about mdxanthine or
mdephedrine were strictly based off of the thought on pharmacological response vs actual chemistry. I had seen many different reports on bioisosteres
of the mdma moiety, but they were only similar to mdma when they were TDMA, a thiodioxy substitute, a selenium one, and a nitrogen one substituted at
the oxygen in "dioxy". However the curiosities about the ones I stayed were merely sitting in my mind for years and years. I definitely don't like
having my time wasted, so again, please accept my apologies. I will be very cautious to remember to keep it chemistry based and not based off of
pharmacology of one substance and the addition of the component that I believed made the other substance widely known for its effects. If someone had
actually followed my curiosity and then tested it on someone it could've killed them and in a nasty way. Not my intentions AT ALL. Thanks
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jackchem2001
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Phenyl esters have anhydride-like pi character and so are not very stable. At some point I want to try making para-nitrophenol acetate to use as an
acylation agent, but that is aside from this thread.
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