Triflic Acid
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Synthesis of N-methylimidazole
I have imidazole, and am going to make N-methylimidazole by reacting it with MeI and then NaOH. What solvent should I use for this reaction?
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Texium
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DCM should work well.
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Triflic Acid
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Just out of curiosity, did you find that in a prep? If so, could you give a link or something?
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Boffis
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I would try water or methyl alcohol first.
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Texium
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No, just my
intuition.
I don’t think water would be great considering it will react
with the methyl iodide and it’s annoying to evaporate. Methanol sounds good though.
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