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pneumatician
Hazard to Others
Posts: 412
Registered: 27-5-2013
Location: Magonia
Member Is Offline
Mood: ■■■■■■■■■■ INRI ■■■■■■■■■■ ** Igne Natura Renovatur Integra **
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the problem here is when animals and cel cultives , o surprise, receive the "placebo effect"
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unionised
International Hazard
Posts: 5128
Registered: 1-11-2003
Location: UK
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Mood: No Mood
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That problem is called publication bias
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Chemosynthesis
International Hazard
Posts: 1071
Registered: 26-9-2013
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Unionized is right. I know this guy is a troll, but I guess other people might read this anyway. First, methodologies are very important. I can
stimulate phosphoERK in a cell line by banging on my table before taking a measurement.... Cell lines are not whole organisms, and have many potential
problems.
And animal models are not humans. The diseases we model in them are rough approximations of those in people, and choosing them is very complicated.
I've talked a little on it elsewhere, but I am not an animal model specialist. I just know enough problems with them to leave any of that kind of
thing to someone else.
This is why most drugs fail in clinical trials, often late, in humans after very promising results in other stages. There is a joke in biomedical
disciplines that "every disease has been cured... in mice" for a reason.
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