Intergalactic_Captain
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I need a new drug...
I wasn't quite sure how to title this, so I figured I'd go for pink floyd lyrics... Anyway, I have a five page paper due on friday for my bio class.
The assignment is to pick a drug, any drug, and write about its effects and side effects. The problem is, I have no idea what to write about. I was
thinking about an anticholinergic, but I don't think I could wrap it up in under ten pages.
Anyone have an idea for an interesting drug that'll wrap up nicely? Or a class of drugs that might have a hidden gem? I'll pick the best Idea I find
by noon or so tomorrow if anyone cares to help.
If you see me running, try to keep up.
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Ozone
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Pink Floyd? I thought that was Huey Louis "I want a new drug, one that won't make me sick..."
Good choices (intentionally avoiding illicit pharmies):
Lidocaine: Prodrug was cocaine (so, an interesting story), most typical synthesis used in most college organic labs.
Prozac: Possibly the largest blockbuster; you could discuss side effects including...suicidal tendencies and erectile disfunction.
Disulfuram: A dithiocarbamate used for detoxing alcoholics--renders alcohol dehydrogenase ineffective. Result, barfing drunk for days.
Physostigmine: A deadly toxic AChE inhibitor (anti-cholinergic) derived from Physostigma Venenosa (I think) which is used as an antidote for
atropine/scopalomine, etc. poisoning. I would go with this one for an AChE inhibitor paper given in most schools (does not pack the "nerve gas" vibe).
Thalidomide: Cause of phocomelia in infants when given to european mothers to quell morning sickness (only one stereoisomer does this; it was served
as a racemate ). Now used to treat leprosy, I believe. Fascinating history *and*
wakeup call for the FDA. Also of interest is that the effect only occurs when the drug is adminstered in a narrow gestation window.
Viagra: 'Nuff said. With Cialis, another 'fil, side effects include delayed back pain and muscle stiffness; I thought those were *results* not side
effects .
Naloxone: Opioid antagonist. Used to immediately detox opiate addicts, and to stabilize OD's.
Digoxin: From Foxglove, applied as a cardiotonic. Extremely toxic when applied over the therapeutic titer.
The list goes on-and-on, but, I have to stop somewhere!
Good luck,
O3
-Anyone who never made a mistake never tried anything new.
--Albert Einstein
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Intergalactic_Captain
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I do believe you're right...That was Huey Lewis and The News. I've got to listen to less pink floyd...
Physostigmine sounds interesting...And I'm not worried about writing about the wrong thing, this is a university class - I know its a short paper, but
my professor's got an odd grading system.
keep em' coming though, if anyone has anything else.
If you see me running, try to keep up.
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Baphomet
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What about aspirin?
and I like 03's Disulfuram idea, it'd be an interesting one to look at
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haribo
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If your going for disulfiram, why not also investigate 1 amino cyclopropanol (found in some mushrooms) which has a similar effect. 2 different
chemicals (not even similar) same result...
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Intergalactic_Captain
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I ended up waiting too long to do proper research and had to pick something easier. I ended up doing heroin...I never figured googlebooks would give
me more turn of the century literature than the journals UB subscribes to. Most of the good research stopped around 1924, but the oldest journal
article I was able to find on it was from the 1960's...
But, I did learn a good bit more about the history of aspirin...
If you see me running, try to keep up.
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nightflight
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Heroin? very controversial amid public address, but not really in science circles, anymore.
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gil
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Though this is BIOchem, why not toxins from Hypnozoae?Time it's just about right, and:do you have UmmaGumma? There's a nice bit whith birds
screamings!Mucho gusto! I had ,3/4 days ago, the most beautyfull tatto on my hand!!SHAPE MORPHING!!!shame it didn't last, like all the patterns
around! I'm waiting the next moon to see if I can get the 3' wave! hope not wait 11 years!!
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Ozone
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WTF was that?
!No comprendo su palabras!
Bueno suerte,
O3
-Anyone who never made a mistake never tried anything new.
--Albert Einstein
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unionised
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I don't think gil needs any more new drugs OTOH he might just need less Pink Floyd.
[Edited on 4-12-2006 by unionised]
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Baphomet
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hehe gil's posts have popped up here and there. i'm left wondering if he's for real or just taking the piss.. i mean if someone's that baked how can
they even find the keyboard?
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JohnWW
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How about cathinone, the main active component of qat or khat (catha edulis), which is native to tropical east Africa, although it grows in a wide
range of climates?
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gil
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No copro la my palpebra? I'll be circumcise: Hypnozoa(ARCHEA) le carote genera will get you HI. aritmetically garanty!
OK, I'll try be SIRIUS from now on.I'll post some accademial papers as soon as I get thinks sorted.Wait the now!
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nightflight
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| Quote: | Originally posted by JohnWW
How about cathinone, the main active component of qat or khat (catha edulis), which is native to tropical east Africa, although it grows in a wide
range of climates? |
Isn´t cathinone norpseudoephedrine?
I think the Dislufuram-way of treating social-issue-born behaviour and problems, is the new way of treatment, that found its way from the WW2
concentration camps, and the mob, to modern medicine. 
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unionised
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No, it's the corresponding ketone.
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Sauron
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Get a physician's desk reference (PDR)
Open to any page.
Pick a therapeutic agent at random.
Or go with Puromycin
Antibiotic, with some interesting side effects on labile memory storage.
Or AZT, there's a socially relevant one
Or 5FU, that's 5-fluorouracil
Potent cancer chemotheraputic.
Or experimental TAU triacetyluridine.
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