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KFC
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Synthesis Phenol
If you neutralize Salicylic Acid with Sodium Hydroxide does it make Phenol?
Life Is Like A Bucket Of Chicken
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Sandmeyer
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Why are you posting this here and not in the beginings forum? Read the faq, do at least some own research before asking to be spoonfed. Your question
can be answered by consulting any general organic chemistry book, online as well as offline.
[Edited on 4-11-2006 by Sandmeyer]
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KFC
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All you have to say is yes or no.
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DeAdFX
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| Quote: | Originally posted by Sandmeyer
Why are you posting this here and not in the beginings forum? Read the faq, do at least some own research before asking to be spoonfed. Your question
can be answered by consulting any general organic chemistry book, online as well as offline.
[Edited on 4-11-2006 by Sandmeyer] |
You don't need to know organic chemistry to realize that an acid and a base form a salt and water.
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enhzflep
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Ahh, but that's exactly the point. Had said research been carried out before posting, then the question would never have been asked.
Nor would it 'have' to be answered.
If you don't understand calculus and have tried your best at it, no-one will begrudge you for asking for a few pointers. On the other hand, If one was
to ask 'What's 1+1?' or 'What's 7*16?' then one could expect a response that was somewhat frosty, if there at all.
KFC, I understand your point of view - It takes almost no time to read or answer, HOWEVER when one compares the several minutes you may save by asking
in such a forum with the amount of time spent reading the post be each and every person that comes across it, then it quite quickly takes (us) more
time than it saves (you).
Look, don't get me wrong - I've got no idea if your synth would work. But searching for text that is already there is THE way to go. If this turns up
no results, AND there's not a post that is appropriate then by all means - start a thread and ask away.
Regards.
EDIT: Crap! DeAdFX beat me to the punch. Of course acid+base = salt + water. I really must go to sleep overnight more often..
[Edited on 4-11-2006 by enhzflep]
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KFC
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All you have to say is yes or no.
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Sandmeyer
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Hey, asshole, all you have to do is to respect the forum, then maybe someone will help you...
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KFC
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| Quote: | Originally posted by KFC
All you have to say is yes or no. |
Sorry about this, my internet is screwy.
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YT2095
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| Quote: | Originally posted by KFC
If you neutralize Salicylic Acid with Sodium Hydroxide does it make Phenol? |
KFC, at least TRY and work this out for yourself!
forget that it`s Salicylic acid, what if it was Sulphuric or Nitric acid, what would it make then?
now just change the suffix for either of those and you have your answer.
now having arrived at your answer, does it sound anything like Phenol to you?
\"In a world full of wonders mankind has managed to invent boredom\" - Death
Twinkies don\'t have a shelf life. They have a half-life! -Caine (a friend of mine)
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Mr_X
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| Quote: | Originally posted by KFC
If you neutralize Salicylic Acid with Sodium Hydroxide does it make Phenol? |
Nope, it will make sodium salicylate.
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KFC
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How do I make Phenol from Salicylic Acid?
And Thank You Mr_X
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woelen
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KFC, the way you behave in this thread will make your life over here on sciencemadness not very pleasant. If you continue acting like this, then you
will simply be ignored by other members.
Show us, what you have found already on the properties of phenol and/or salicylic acid. Do you have some ideas of your own? Show that you can do some
research yourself. If you provide us with input, then we will get more of a discussion, instead of just a spoonfeed session. Also, if you are really
interested in the subject, then I strongly urge you to do some research, because it also gives you general knowledge, which comes in handy in many
other situations. I built up my knowledge not by being spoonfed, but by actively reading, searching the Internet, experimenting and finally asking
questions on forums. But this is the order in which things should be done.
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The_Davster
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| Quote: | Originally posted by woelen
Show us, what you have found already on the properties of phenol and/or salicylic acid. Do you have some ideas of your own? Show that you can do some
research yourself. If you provide us with input, then we will get more of a discussion, instead of just a spoonfeed session. Also, if you are really
interested in the subject, then I strongly urge you to do some research, because it also gives you general knowledge, which comes in handy in many
other situations. I built up my knowledge not by being spoonfed, but by actively reading, searching the Internet, experimenting and finally asking
questions on forums. But this is the order in which things should be done. |
If you don't show some of this in your next post KFC this thread is going to detritus.
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laekkerBoy
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Phenol Preparation - Question
Hey guys!
I am in kind of a trouble right now. I am planning on making a batch of TCPO and the only thing remaining in my process of synthesizing it, is the
2,4,6-Trichlorophenol. Making the TCP is not the problem, since it is rather easy and simple when starting from phenol. But making the phenol is
difficult for me. I have been searching and thinking around for about two weeks now and my mind is fu*king up right now.
So here comes the question: Do you know of a rather easy way to prepare phenol? I was hoping that you could tell me a way starting from toluene, which
I can get very cheap and very pure, and going further on to benzene. I really don't have any restrictions for the process, except from dealing with
very high temperatures.
If it is a problem starting from toluene, I am willing to start from acetylene which I can get very easily too.
I am looking so much forward to your reply and thanks in advance!
The Kindest Regards,
Christian
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mnick12
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Make phenol? Why not just buy some? After all it is rather cheap especially in the quantities you will need. But making it from either toluene or
acetylene would be very tough and require alot of steps. I would do a decarboxylization of salicylic acid which is also cheap, and can be easily made
from aspirin.
How do plan on chlorinating your phenol?And how do you know your final product is going to be 2,4,6-trichlorophenol and not some other polychlorinated
phenol? Chlorinations are not very easy to control, and there is a very good possibility that your phenol will end up have PCB's and other very nasty
and very carcinogenic polychlorinated phenols. You are probably better off just buying some.
Good luck, are you doing the glow stick reaction?
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Jor
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Start from sodium benzoate. When this is heated in a metal vessel benzene vapours evolve, wich should be condensed.
http://www.sciencemadness.org/member_publications/benzene_pr...
It should be redistilled due to impurities such as biphenyl.
Next nitrate this (Vogel) to nitrobenzene.
Reduce this to aniline with Sn/HCl or Fe/HCl, or best dithionite, by wich you avoid messing with the metals.
Diazotise, to obtain phenol (see Vogel).
But this is a a lot of work and yields aren't great. Are you sure you can't obtain phenol. It is sometimes sold on ebay as carbolic acid.
Lastly be careful with benzene, nitrobenzene, aniline and phenol. All quite unhealthy compounds.
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JohnWW
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Phenol is made industrially in large quantities, usually by firstly sulfonating C6H6 with oleum (fuming sulfuric acid, H2SO4 + SO3) to obtain
benzenesulfonic acid, and then hydrolyzing this to C6H5OH with NaOH under pressure at 200ºC. It is used for further industrial chemical syntheses, as
a lab reagent, and as the active ingredient of "carbolic soap" which has a distinctive odor of phenol.
It appears to be quite easily chlorinated all the way up to pentachlorophenol (PCP), C6Cl5OH, which is quite strongly acid, and which was once used as
a non-metallic wood preservative, bonding to the cellulose in wood by esterifying the -OH groups. But PCP has since fallen out of favor for this use,
because it is very water-soluble, being leached out of bare wood in the open by rain, and because it is highly liver-toxic and carcinogenic.
[Edited on 11-4-10 by JohnWW]
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Nicodem
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LaekkerBoy, welcome... but please be aware that you will receive more useful replies if you show you did some literature search yourself before asking
others to do so. Even on this forum we have threads on the preparation of phenol. I do not remember if any experiments were described, but I'm pretty
sure some useful reference was given. Also, avoid using acronyms unless you define them on first use. It brings too much confusion and only few will
understand what you meant by TCP or TCPO.
If for some reason you want to prepare phenol yourself instead of just buying it (like other reagents you will need), then obviously doing it from
salicylic acid (hydrolysed aspirin) is the simplest way. But if you need just any oxalate for a luminiscence experiment you might use some for which
you need no stinking and toxic 2,4,6-trichlorophenol, for example:
| Quote: | Synthesis of bis(6-butoxycarbonyl-2,4,5-trichlorophenyl)oxalate.
Li, Bin; Miao, Weirong; Cheng, Lubo.
Jingxi Huagong, 15 (1998) 23-25. (in Chinese)
Chem. Abstr. 128, 243798:
The title compd. was prepd. from chlorination of salicylic acid in acetic acid then in oleum giving 3,5,6-trichlorosalicylic acid, which was
esterified with butanol and treated with oxalyl chloride. The title compd. is one of the necessary aryl oxalates used in chemiluminescent device.
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The similar synthesis of 3,5,6-trichlorosalicylate esters from salicylic acid is described also in US4308395 (in English).
PS: When opening threads without any references given, please do so in the Beginnings section (where it is being moved anyway).
Edit: Did some literature search.
[Edited on 11/4/2010 by Nicodem]
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unworthy of the scientist. Some of the greatest men of science have publicly repudiated a theory which earlier they hotly defended. In this lies their
scientific temper, not in the scientific defense of the theory. - Weston La Barre (Ghost Dance, 1972)
Read the The ScienceMadness Guidelines!
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Nicodem
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Thread Moved
11-4-2010 at 14:25 |
chemrox
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Good for you Nicodem. That was kind, thorough and very professional.
I edited this post to include the following 'green' synthesis.
http://www.aist.go.jp/aist_e/latest_research/2002/20020109/2...
[Edited on 12-4-2010 by chemrox]
"When you let the dumbasses vote you end up with populism followed by autocracy and getting back is a bitch." Plato (sort of)
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laekkerBoy
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Thanks a lot everyone!! Really, I am grateful!
After posting this thread, I have learned that the easiest way to synthesize Phenol is by the following route:
Toluene --(Friedel-Crafts)-->
Benzene --(Chlorination)-->
Chlorobenzene --(Raschig-Hooker)-->
Phenol.
I hope that this can help you guys too! I'll promise to post some pictures or a video of my reaction when I am able to do it.
As for the chlorination of Phenol to 2,4,6-Trichlorophenol, I am going to use a method previously posted on this forum:
| Quote: |
Originally posted by not_important at:
http://www.sciencemadness.org/talk/viewthread.php?tid=6757#p...
For 2,4,6-TCP just mix phenol with about 5 times its volume of dilute HCl, warm slightly to get the phenol to form a solution, then bubble Cl2 through
the mixture with stirring; TCP will precipitate out. Set up your chlorine generator to make 3 moles of Cl2 for every mole of phenol. Remember it's
forming HCl, the solution will grow more acidic. Filter off the TCP and wash with cold (ice) water. Recrystallise from boiling water or water+alcohol
solution (it's really soluble in MeOH, EtOH, and acetone). Extra purification might be crystallisation from hot ligroin or similar hydrocarbon, or
fractional freezing where impurities tend to remain in the liquid portion. There's got to be a number of references around for preparing it.
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Nicodem: I am sorry for that I didn't tell any pages or so with literature. I'll remember that for the next time.
I think that the salicylic acid way is too expensive when you think of the final product, but thanks anyways!
A final applause to all of your guys who have answered my question!!
The Kindest Regards,
Christian.
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not_important
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The Raschig phenol process is little used nowadays, having fallen out of favour in the 1970s. As it takes place in the vapour phase at temperatures
in the low-to-mid 400 C range, and with incomplete conversion, it is not too convenient for amateur application; it really is an industrial scale
process.
The older method using fusion of benzenesulfonic acid with alkali hydroxide is easier for small scale production. Even though the temperatures used
are in the same range, it's much easier to to melt and stir a few hundred grams of reactants than to pass them over catalysts as gases.
Toluene to benzene via FC catalyst works, but can be tedious. Benzene chlorination isn't too bad, but then you're faced with the hydrolysis issue.
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laekkerBoy
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Thanks a lot for the suggestion!
I am unfortunately not able to obtain sulfonic acid ATM to synthesize the benzenesulfonic acid. If i was, it would probably be my preferred way of
obtaining Phenol, so thank you very much!
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DJF90
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Well for a start, you don't use sulfonic acid to synthesise benzenesulfonic acid... Paracetamol is a convenient OTC source of p-aminophenol (by
hydrolysis after extraction) which can then be diazotised and heated in ethanol to effect reduction to phenol. This can then be trichlorinated under
appropriate conditions to the desired compound. Ok its a bit round the houses, but it'll work nicely and provide you with the compound you desire from
relatively easy to obtain starting materials.
[Edited on 21-4-2010 by DJF90]
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UnintentionalChaos
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Try the orgsyn prep for p-hydroxybenzoic acid. One equivalent of phenol distills off during heating and can probably be condensed readily if desired.
Salicylic acid and potassium carbonate are readily available.
[Edited on 4-21-10 by UnintentionalChaos]
Department of Redundancy Department - Now with paperwork!
'In organic synthesis, we call decomposition products "crap", however this is not a IUPAC approved nomenclature.' -Nicodem
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laekkerBoy
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Thank you! I'll try to find something about that.
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