stygian
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Nitrile to ketone? with EtMgBr
What is/are the intermediates formed from methadone nitrile and EtMgBr, to eventually yield the ketone?
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chochu3
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Are you asking for the mechanism or what is the product after 2,2-Diphenyl-3-methyl- 4-dimethylaminobutyronitrile reacts with the grignard reagent?
After the grignard is reacted with the nitrile above it I believe is methadone at that point.
\"Abiding in the midst of ignorance, thinking themselves wise and learned, fools go aimlessly hither and thither, like blind led by the blind.\" -
Katha Upanishad
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stygian
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I was wondering about the intermediate
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turd
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A metalloimine R=NMgCl.
Come on, don't you have any OC-textbook or even google?
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