rockyit98
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Registered: 12-4-2019
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single pot synthesis of CATECHOL from benzene
Catechol is produced industrially by the hydroxylation of phenol using hydrogen peroxide.
C6H5OH + H2O2 → C6H4(OH)2 + H2O
but Fenton's reagent is also used in organic synthesis for the hydroxylation of arenes in a radical substitution reaction such as the classical
conversion of benzene into phenol.
C6H6 + FeSO4 + H2O2 → C6H5OH
can i combine two in to one reaction?
i got this image from wiki https://eo.wikipedia.org/wiki/Katekolo
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Metacelsus
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I expect if you add iron, you'll get a messy mixture of over-oxidized products. Fenton's reagent is quite a harsh oxidizer. For the industrial process
see here: https://sci-hub.tw/10.1002/14356007.a19_313
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