morsagh
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alpha aminoacids
Please guys, can you give me some links for full procedure of alpha-aminoacid synthesis? I can´t find anything about synthesis through
alpha-haloacids.
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Nicodem
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Thread Moved
26-5-2016 at 12:19 |
DJF90
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One of the common methods is Strecker synthesis, whereby an aldehyde is treated with an ammonia source and alkali cyanide salt to afford the
alpha-amino nitrile, which is then hydrolised to the alpha-amino acid. The intermediate a-aminonitrile may also useful for further elaboration.
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zed
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http://www.orgsyn.org/demo.aspx?prep=CV1P0298
Two methods are given herein. Seems to me, in most cases, yields are better.....utilizing alpha-BROMO-acids.
Further:
https://books.google.com/books?id=qSnSCgAAQBAJ&pg=PA1041...
[Edited on 26-5-2016 by zed]
[Edited on 26-5-2016 by zed]
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Eddygp
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The Strecker synthesi is the classical approach, but you need a cyanide salt.
there may be bugs in gfind
[ˌɛdidʒiˈpiː] IPA pronunciation for my Username |
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morsagh
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I want some papres where is hell-zelinsky synthesis.
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