kyanite
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diekmann ring closure
Have any of you guys heard of this mechanism? I saw it in a colledge book once, but the pictured only showed a secondary amine, with the same chain on
each side with carboxylgroups, and i think sodium ethoxide reacting to form a cyclohexane type structure...
Google kills my initiative with all those dam pdfs... plus, most either talk
about pyridine type compunds being made from other rings. Any help would be appretiated
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Marvin
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The amine itself has essentially nothing to do with the reaction. Try looking at,
http://orgchem.chem.uconn.edu/namereact/dieckmann.html
and,
http://themerckindex.cambridgesoft.com/TheMerckIndex/NameRea...
As the Merk says, its an intramolecular claisen condensation. If you are after a mechanism, look up claisen.
Assume by pyridine compounds you mean fused to other rings (like a quinoline), rather than a seperate ring. This is a shame because I'm after a
good way to make pyridine.
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kyanite
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Thats the one!, well, the second link to be exact, it looks exactly like the
reaction i saw... Thank you, that cleared up some questions i had about this method
Yeah, alot of the pdfs had chemicals like that quinoline, but sorry, i dont think i saw a route to pyridine,
dam adobe acrobat with the stupid load errors...
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incitatus
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pyridines are normally made via a Hantsch synthesis
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