yogi
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Trimethoxy-Cathinone
OK, so I know these analogs have been synthesized. I do not know of any literature concerning this, and if anyone has any refs it would be nice if
posted here.
I believe these analogs will prove to be quite useful in research (at least some of them)
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Zephyr
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nope sorry couldn't find anything. How would they be useful in research?
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turd
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Quote: Originally posted by yogi  | | OK, so I know these analogs have been synthesized. I do not know of any literature concerning this, and if anyone has any refs it would be nice if
posted here. |
Go to a library/university with SciFinder/Reaxys access.
| Quote: | | How would they be useful in research? |
Structure activity/function relationship. Possibly the most important aspect of applied synthetic chemistry.
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chemrox
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visit MAPS
BTW: tm-amphetamine turned out to have little or no activity (PiKHAL) so I'm not optimistic about tm-cat
[Edited on 15-11-2013 by chemrox]
"When you let the dumbasses vote you end up with populism followed by autocracy and getting back is a bitch." Plato (sort of)
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Mildronate
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Do you need literature about activity or synthesis, synht is similar to other cathiones
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zed
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The way I remember it, TMA made folks want to punch other peoples faces in. Not generally a quality one looks for in psychoactive materials. Unless
of course, you are considering military applications.
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Rich_Insane
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This compound would most likely not be all that active. I don't think substitution in the beta position would do anything for 5ht2a affinity (the
primary target of the TMA series). Beta-keto compounds like beta-keto-methamphetamine (methcathinone) or beta-keto-3,4-methylenedioxymethamphetamine
("Methylone") have enhanced noradrenergic activity, in particular, noradrenaline release and reuptake inhibition (if I recall correctly).
Putting an oxygen in that position would not enhance activity to an appreciable extent, and might just decrease activity (less BBB penetration?)
Synthesis could be performed starting from 2,4,5-trimethoxyphenyl-1-propanone (sorry IUPAC for butchering nomenclature).
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bfesser
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Thread Moved
27-11-2013 at 12:20 |
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