Sciencemadness Discussion Board
Not logged in [Login ]
Go To Bottom

Printable Version  
Author: Subject: phenylacetonitrile synt from Pihkal
stimo-roll
Harmless
*




Posts: 18
Registered: 13-1-2007
Location: easteuropa
Member Is Offline

Mood: No Mood

[*] posted on 15-12-2007 at 05:53
phenylacetonitrile synt from Pihkal


Hi. Interesting reaction for preparation phenylacetonitriles - http://www.erowid.org/library/books_online/pihkal/pihkal147.... Substituted bromobenzene reacted wia strong base (LDA) give yne-derevate, which reacts wia acetonitrile give subst-phenylacetonitrile. Anybody know this type reaction examples in literature? Can LDA be replaced with t-BuOK?

[Edited on 15-12-2007 by stimo-roll]

[Edited on 15-12-2007 by stimo-roll]
View user's profile View All Posts By User
stoichiometric_steve
National Hazard
****




Posts: 827
Registered: 14-12-2005
Member Is Offline

Mood: satyric

[*] posted on 15-12-2007 at 08:21


why bother, when it is clearly stated that it is not easy to purify the resulting mixture of products - and the yield is also shitty.
View user's profile View All Posts By User
vulture
Forum Gatekeeper
*****




Posts: 3330
Registered: 25-5-2002
Location: France
Member Is Offline

Mood: No Mood

[*] posted on 15-12-2007 at 11:41


t-BuOK is not basic enough. And we don't like cookery threads here...



One shouldn't accept or resort to the mutilation of science to appease the mentally impaired.
View user's profile View All Posts By User

  Go To Top