alexboc
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What is the functions of chiral synthesis?
Chiral synthesis (enantioselective synthesis, also called asymmetric synthesis) is the synthesis of a compound by a method that favors the formation
of a specific enantiomer or diastereomer. Can anybody explain the functions of chiral synthesis? Thanks.
Reference: https://www.bocsci.com/chiral-synthesis-and-resolution.html
[Edited on 29-3-2018 by alexboc]
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elementcollector1
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Sounds like someone's got a homework problem.
Elements Collected:52/87
Latest Acquired: Cl
Next in Line: Nd
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j_sum1
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Entaniomers ate critical in biological systems since many biochemicals must physically interlock in order to function.
But really, why do you ask? If we knew the context that prompted the question then we could answer more specifically. Until then this looks like
fishing for homework answers or circumventing personal effort.
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j_sum1
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Thread Moved
29-3-2018 at 02:03 |
LearnedAmateur
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There isn’t really much to explain for it, it’s a procedure for making a single enantiomer of a chiral compound as opposed to the racemic mixture.
I could give one example, thalidomide - one enantiomer provides the medicinal benefits whereas the other caused birth defects which gave the compound
its infamous status hence chiral resolution is essential in this case. Like J_sum1 said, they matter for biological processes so it’s an important
topic in pharmacology because many enantiomers produce varied changes in the body, to their counterparts.
In chemistry, sometimes the solution is the problem.
It’s been a while, but I’m not dead! Updated 7/1/2020. Shout out to Aga, we got along well.
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PhenethylamineMachine
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Another good pharmacological example is L-methamphetamine.
The levorotatory enantiomer of methamphetamine, L-methamphetamine, is an over the counter sympathomimetic vasoconstrictor, while the dextrorotatory
enantiomer of methamphetamine is a powerful illicit euphoric stimulant.
So, in this case, one enantiomer is a useful and benign pharmaceutical, while the other is a destructive illicit substance of abuse.
Different enantiomers of chiral molecules possess different properties.
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