soma
Hazard to Others
Posts: 297
Registered: 31-7-2010
Member Is Offline
Mood: No Mood
|
|
Synthesis of Ascorbic Acid
I read that the "Osone - Cyanide" method of synthesis of ascorbic acid is the best and simplest.
| Quote: | Conversion of sugars into the corresponding osones is readily brought about by the wtiori of alcoholic cupric acetate.
Without further purification, these osones may be converted into ascorbic acids by condensation with potassium cyanide
followed by hydrolysis with dilute mineral acid. If carried out at 95" rather than 45-50' as formerly prescribed the hydrolysis
can be completed in 3 hours instead of 1-2 days. |
-- Synthesis of Ascorbic Acids by the Osone—Cyanide Method1
J. Kelvin Hamilton, F. Smith
J. Am. Chem. Soc., 1952, 74 (20), pp 5162–5163
Opinions?
|
|
|
Sulaiman
International Hazard
Posts: 3696
Registered: 8-2-2015
Location: 3rd rock from the sun
Member Is Offline
|
|
The obvious question;
If the salicylic acid (or derivatives such as wintergreen) is intended for use on sentient beings,
can you be certain that no cyanide(s) will end up in your final product ?
CAUTION : Hobby Chemist, not Professional or even Amateur
|
|
|
soma
Hazard to Others
Posts: 297
Registered: 31-7-2010
Member Is Offline
Mood: No Mood
|
|
Ascorbic acid = vitamin C.
Many plants contain small amounts of cyanide. E.g. types of bean sprouts, carrots, celery, wheatgrass, yams, brown rice, butter beans, lima beans and
mung beans.
(They contain amygdalin which releases cyanide in contact with acid.)
|
|
|
XeonTheMGPony
International Hazard
Posts: 1640
Registered: 5-1-2016
Member Is Offline
Mood: No Mood
|
|
Don't forget peach pits and apple seeds.
|
|
|
soma
Hazard to Others
Posts: 297
Registered: 31-7-2010
Member Is Offline
Mood: No Mood
|
|
And, of course, apricot kernels.
[Edited on 16-9-2017 by soma]
|
|
|
unionised
International Hazard
Posts: 5126
Registered: 1-11-2003
Location: UK
Member Is Offline
Mood: No Mood
|
|
Since the product is an acid any cyanide present would be converted to HCN (which is a very weak acid) and would be lost by evaporation.
The person doing the synthesis might kill them self, but the final product would be relatively safe.
|
|
|
![[*]](images/xpblue/default_icon.gif){kind=icon}
