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Author: Subject: Alternatives to Hofmann rearrangement
parabola
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[*] posted on 24-2-2015 at 11:27
Alternatives to Hofmann rearrangement


Can anyone suggest another reaction which also rearranges an aromatic primary amide to a primary amine with one less carbon atom?
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solo
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[*] posted on 24-2-2015 at 16:34


......make the carbamate then hydrolyse to the desired amine....solo/java



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[*] posted on 6-6-2016 at 12:56


I removed all the posts related to nonsensical insinuations on account of parabola's intentions. Please restrain on accusing new members of being drug cooks when the question shows nothing of this kind.

Alternatives to Hoffman rearrangements are all the related rearrangements:
Curtius rearrangement
Lossen rearrangement
Schmidt rearrangement




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