Hey There
Harmless
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Registered: 20-3-2014
Location: Washington
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Piperonyl Butoxide to Safrole?
Is there a way to cleave the ether on the alpha carbon without damaging the methylenedioxy ring? And how about the double bond on the propyl side
chain to form Safrole?
 
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Chemosynthesis
International Hazard
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Might be possible to strongly oxidize those alkyl chains to dibenzoic acid, decarboxylate both, halogenate, resolve products, Friedel Crafts alkylate,
then re-etherify the cleaved bridge from the vicinal diphenol. Why do you ask?
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leu
Hazard to Others
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Retrosynthesis
Piperonyl butoxide is made by etherification and chloromethylation starting from dihydrosafrole which is derived from safrole  Hoping to cleave one ether without cleaving another is what is known as wishful
thinking  The question posed should be are any of these reactions reversible
with a change of equilibrium  That's the answer and the end really does result
from the effort applied 
Chemistry is our Covalent Bond
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Nicodem
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Thread Moved
5-4-2014 at 10:29 |
zed
International Hazard
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No way Jose.
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