chemrox
International Hazard
Posts: 2961
Registered: 18-1-2007
Location: UTM
Member Is Offline
Mood: LaGrangian
|
|
going semi-micro
Is 14 mm ST semi-micro? Anyway I'm moving toward the 1 mmol from the 10 mmol experimentation level. I have a lot small flasks and a good partial
takeoff vacuum still head. I don't have a column, condenser or simple still head. Another issue is workup. At the 1 mmol level I think
chromatography is going to work a lot better than distillation and recrystallization. Maybe I need one of those "baggy pants" Hickman condensers for
simple distillation. But a smaller flash chromatography setup would seem a must. This could become rather expensive in terms of stationary phase
replacement. Or running lots of solvent through to clear out residual tars and the like. Comments? Advice?
Thanks!
"When you let the dumbasses vote you end up with populism followed by autocracy and getting back is a bitch." Plato (sort of)
|
|
|
radagast
Hazard to Self
Posts: 79
Registered: 28-6-2012
Location: NYC
Member Is Offline
Mood: No Mood
|
|
Chromatotron
How about using a Chromatotron or Cyclograph to purify ~100 mg. to 1 gram of product? I've played around with one and you rarely need more than a few
hundred mls of solvent, and you can reuse (and easily make) silica or alumina plates.
|
|
|
![[*]](images/xpblue/default_icon.gif){kind=icon}
