morphinan ponderings
and thoughts, that IS the configuration of the piperidine ring alone ,responsible for the almost nil mU activity? This construction built like a
brick house, not to even mess with. Would the same probably necessarily hold true with an even more ornamented morphinan, as well. Say certain C-14
ligands, or even Bentley type compounds sticking straight down (etorphine/buprenorphine).
All the time, maintaining the original + chirality of the very stripped down compound. But pondering perhaps, other optically active sights due to
add-ons. Just curious.
not talking levo
[Edited on 19-8-2012 by Fennel Ass Ih Tone]
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