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Author: Subject: Reaction of 1-Phenyl-2-chloropropane with methylamine?
sadafag
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[*] posted on 8-11-2011 at 04:04
Reaction of 1-Phenyl-2-chloropropane with methylamine?


Does 1-Phenyl-2-chloropropane[http://www.chemindustry.com/chemicals/02145596.html]
could react with methylamine and give methamphetamine?
Is it even possible without fancy catalysts?
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[*] posted on 8-11-2011 at 08:34


I believe so, however i'm not positive. Also the members on this board aren't fond of "people like you", no offense.
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Nicodem
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sadafag
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[*] posted on 8-11-2011 at 10:24


I think i found an answer, check M6[?]
http://docs.google.com/viewer?a=v&q=cache:joLPGiYqausJ:w...
I think it's reliable site, so we could close this topic.


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[*] posted on 9-11-2011 at 05:47


it is sterically hindered thus causing a bad yield.



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[*] posted on 12-11-2011 at 00:19


Nevermind...

[Edited on 12-11-2011 by madscientist]




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sadafag
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[*] posted on 21-12-2011 at 15:32


Maybe the better group would be bromide group, as it is better leaving group thus reaction yield will be higher?

And please explain these words: "it is sterically hindered thus causing a bad yield."
?



[Edited on 21-12-2011 by sadafag]
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[*] posted on 21-12-2011 at 16:15


READ!


http://en.wikipedia.org/wiki/Stereoisomerism
http://en.wikipedia.org/wiki/Stereoselectivity




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[*] posted on 21-12-2011 at 16:49


I think i found an answer, check M6[?]
http://docs.google.com/viewer?a=v&q=cache:joLPGiYqausJ:w...
I think it's reliable site, so we could close this topic.

Those reactions will not work as written you cannot just mix those things together and expect to get the product, I am not sure of your level of chemistry knowledge...but if you think that the appendix you just linked is the answer you were looking for I would go research some more.
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