conducter - 24-3-2007 at 22:56
a synth i saw once called for "diluted aqueous methylamine in 150 mL alcohol"
does this mean 10% methylamine in water, then add this solution to 150ml alcohol?
But the main question is, there are many routes to methylamine hcl. But what is needed is Methylamine aqueous solution for creating a nitropropene.
How would one go about making a diluted aqueous methylamine solution from methylamine hydrochloride?
12AX7 - 24-3-2007 at 23:45
Presumably, the amount of water, alcohol and methylamine is specified somewhere...
I would suspect you can form it in situ by adding NaOH to MeNH3Cl in alcohol. NaCl precipitates. Some H2O forms, too, but...solubility for NaCl
should still be low huh?
This won't work in H2O since the NaCl won't precipitate very well.
If an NaCl or NaOH impurity cannot be tolerated, then probably your best bet is to freebase and absorb the MeNH2 into the H2O/alcohol solution.
Tim
conducter - 25-3-2007 at 15:13
the reaction is for a synthesis of phenyl-2-nitropropene.
N-butylamine cannot be found easily, neither can cyclohexylamine, but another synth calls for methylamine solution.
Would a p2np synth from benzaldehyde, nitroethane be able to use methylamine hcl or is only the freebase usable?