Sciencemadness Discussion Board

Synthesis of 1,3,5,7-Cyclooctatetraene

Shob dhillon - 6-10-2017 at 23:20

I am trying to synthesize 1,3,5,7-Cyclooctatetraene for a project, and I don't know what would be the easiest synthesis pathway. I have an abundant amount of Calcium Carbide, and there are some well-known ways of making Cyclooctatetraene from acetylene.

There is a process which uses acetylene, Nickel Cyanide and requires high pressure (which I can't do): http://onlinelibrary.wiley.com/doi/10.1002/jlac.19485600102/...

There is another way to produce 1,3,5,7-Cyclooctatetraene, which uses Acetylene coupling on Cu(111).This has very low yield, but is still works and the problem is that I don't know how to make Cu(111) catalyst.

https://www.ncbi.nlm.nih.gov/pubmed/16852333

If someone could please suggest where to buy or how to make Cu(111) that would appreciated. If someone has a cheap supply of Cu(111), I'd be happy to buy it if it is affordable for me.

Could someone suggest any other ways to do this Cyclization?

unionised - 7-10-2017 at 00:18

doubt it's practical, but this is interesting

http://www.sciencedirect.com/science/article/pii/S0168945203...

CuReUS - 7-10-2017 at 09:07

http://pubs.acs.org/doi/10.1021/jo01289a029