monochemist - 16-10-2006 at 04:21
Dear all,
I am working on a project in my thesis to prepare some Organophosaphates compounds, mainly compaunds used as insecticides.
therefore, I need the synthesis methods of organophosphates insecticides to apply it in my project, I hope any one can help?
thanks in advance,
woelen - 16-10-2006 at 06:21
Could you please specify for which university and faculty this thesis must be written? As some of us may know, such organophosphates can be EXTREMELY
toxic and some of them are used as war/nerve gases.
It would be good to know who we are helping with such a question like this.
garage chemist - 16-10-2006 at 08:36
Organophosphates are a vast field of compounds- you will have to specialise somewhat. Look at books which cover the theme (organophosphate
insecticides or something along those lines).
The infamous E 605 (Parathion, more toxic than KCN) is also an organophosphate, one that is derived from PSCl3.
There are a lot of others, which are derived from POCl3 like Tabun (chemical warfare agent), methylphosphonic acid (Sarin, also warfare agent) and
fluorophosphoric acid (Diisopropylfluorophosphate, both a warfare agent and used in medicine as a cholinesterase inhibitor). Those are some of the
most toxic ones.
But there are also a lot of ones with very low toxicity to humans but high toxicity to plants, like Glyphosate (available OTC as the weedkiller
"Roundup". Look up its structure and you will see that it is derived from methylphosphonic acid, just like Sarin).