Maybe Velzee means adding a methyl to one oxygen and an ethyl to the other? If that were the case, that would be pretty difficult, especially for a
beginner. Doing just methyl or ethyl on both sides would probably be doable, using the corresponding alcohol and sulfuric acid.
Another use for 1,3-propanediol would be oxidation to malonic acid. There are multiple methods on the forum, I think, one of them using nitric acid as
the oxidant. |