Omer - 12-3-2016 at 02:00
Hello everyone...
Iam willing to perform mannich rxn with starting material contain a lacton ring...
Using dimethyl amine and formaldehyde with ethanol as solvent
But im wondering... Is it will be possible to obtain product with out using acidic media...
Actually I tried but it failed
failed(I donT know why)is it due to acid absence
And what about lacton ring after ope ING...theoretically it will recycle agin.. Right!?
Actually I dont need to lose other strating material as it took me alot of effords to obtain...
Help pls
MeshPL - 12-3-2016 at 08:07
You want to attatch that dimethylamine and formaldehyde in alpha position next to lactone carbonyl or next to some other carbonyl, it would be helpful
if you named the substrate.