Random - 10-11-2012 at 18:47
I have few grams of amoxicillin and I would like to make some reagents from it.
I would start by breaking that NH bond between hydroxyphenylglycine, but I am not sure which reagents I should use. Maybe HCl would do it? On the
other end of the compound I can't think of any things I could take.
ScienceSquirrel - 12-11-2012 at 09:02
One sniff of acid and theβ-lactam ring will pop apart;
http://en.wikipedia.org/wiki/Beta-lactam#Reactivity
Random - 17-11-2012 at 13:37
Whats are the products? I'm not familiar with these rings.
BlackDragon2712 - 29-9-2016 at 09:27
I don't want to revive an old thread but just in case anyone wants to know what are the hydrolisis products of amoxicilin then here is a good paper
describing its products in acidic, neutral and alkaline conditions.
"New hydrolysis products of the beta-lactam antibiotic amoxicillin, their pH-dependent formation and search in municipal wastewater."
doi: 10.1016/j.watres.2015.11.028
- https://www.ncbi.nlm.nih.gov/pubmed/26613181