i had synthesised chloramphenicol hemi succinate from chormaphenicol but getting poor yield and product was contaminated with raw material as well as
2 other impurity.
kindly suggest me the most possibility of impurity and which probably parameter affect the reaction.
kindly suggest me the most possibility of impurity and which probably parameter affect the reaction.
Provide the references and/or the experimental, else there is no point in making guesses or giving obsolete suggestions.
The only suggestion for side products I can give without any of the required information is the obvious regioisomeric ester and the double succinate
ester.
PS: Please open referenceless threads only in the Beginnings section where I'm moving this.