Quote: Originally posted by oxidativeamination | so in saying that an amide has a very different electron density and charge from an amine, you are saying that it will become pharmacologically
inactive?
so convertion to the amide will effectively decrease or disable ability to cross the BBB?
one more question how does the amide-acetyl linkages stabilty affect its bioavailability? |
Your lack of pharmacology knowledge is only surpassed by the lack of chemical knowledge. This is an honest warning: Please start reading the books and
articles first, or else you are going to hurt yourself. |