Sciencemadness Discussion Board

Trans-Amidification?

GreenD - 31-3-2011 at 08:48

So - we're all familiar with trans-esterification, but I don't get it.

Lets say we want to go from a methyl-ester to an ethyl-ester.

How?

How can you tilt the equilibrium to the right in this case? I'm going to go read the paper I have on this again, but in the mean time can someone explain why (or even if) you can get a major product of the ethyl-ester.

The title is a bit misleading but it's where I'm going eventually.

Nicodem - 31-3-2011 at 09:25

Quote: Originally posted by GreenD  
How can you tilt the equilibrium to the right in this case?

If you check the equation for the equilibrium constant for the transesterification reaction and compare that with the reaction conditions, you will very easily understand why.

PS: It is a local culture to open referenceless threads in the Beginnings section.