I was evaporating water from a mixture of pyridine, glutamic acid, phtalic anhydride and some DMF, and I overshot the temperature and didn't check it
often enough. The whole thing became a light- brown solid mass in the bottom of the RBF, texture a bit like fudgy rubber.
I don't have a clue what I created here, and not a clue about how to dissolve it. I'll try with water and heat, of course, and cheap solvents like
acetone, but I don't know how toxic this is or how to reasonably dispose of it in a responsible way.
What's your bet?
[Edited on 20222222/10/24 by DocX]
[Edited on 20222222/10/24 by DocX]SplendidAcylation - 24-10-2022 at 14:04
Well, I'm not sure how you could get it out of the flask, but in terms of disposal, a good way might be to cut it up into squares and give it to those
pesky trick-or-treating children at Halloween, under the guise of "homemade fudge".
Haha.
But on a serious note, I'm not sure about the toxicity of these things when combined, but you can usually burn things to dispose of them safely.
I have a number of jars full of nasty tarry organic stuff that I plan to burn at some point.Loptr - 24-10-2022 at 14:47
What were you trying to make with the original mixture?DocX - 24-10-2022 at 21:50
What were you trying to make with the original mixture?
N-phtaloyl glutamate. It's an intermediary in thalidomide synthesis. I had done the reaction but got no precipitate when cooling it, so I figured I
would boil off some volume of water. And then I got distracted.
