Would be a pretty cool reaction if it worked, but seems a little unlikely.
As soon as you add base to the reaction you will generate the N-methylaminophenol freebase and sodium sulfate. I don't think that's super soluble in
water, likely precluding any further reactions, at least at room temperature. Not too sure if sodium sulfite is known for it's demethylating abilities
either.
I think p-aminophenol can be generated from Tylenol pretty easily though? |