Sciencemadness Discussion Board

substitute methylamine by propylamine in organic synthesis?

madcow - 19-11-2009 at 10:34

Many organic synthesis uses methylamine , as it is gasous state at room temperature, needs to cool below 6 C , can propylamine ( liquid at room temp) be used instead ? what are the pros and cons?

Thanks.


querjek - 19-11-2009 at 13:09

What do you want to use it for?

madcow - 19-11-2009 at 13:23

to form imine with hydroxy rearrangement of ketone. Thanks.

DJF90 - 19-11-2009 at 14:10

You arent making sense. You want to form the imine? What do you mean by "with hydroxy rearrangement of ketone"?

Nicodem - 20-11-2009 at 00:42

Madcow, you are wrong if you think that posting demented questions is better tolerated than posting questions on how to make ketamine from your made-in-china-precursor. Besides you can not make ketamine if you use anything else but methylamine. Methylamine is a reagent in this synthesis and as such it gets incorporated in the structure of the product. Therefore you can not use propylamine as that would give you a different product.