Sciencemadness Discussion Board

1,2-dihalopropane

chemrox - 3-12-2008 at 19:07

I'm having trouble finding 1,2-dichloro or dibromopropane.

UnintentionalChaos - 3-12-2008 at 20:48

Heat propylene glycol with HCl/HBr and ZnCl2 or ZnBr2. Yields may be shite, but reagents are dirt cheap.

Or run condensed propylene into Bromine in DCM in a dry ice acetone bath until decolorized. That's substantially more complex, but if (and I so no reason why it shouldn't) it works, you'll have clean product after stripping the solvent

You could just bubble the gas through an ice bath with the DCM and bromine but I suspect you'll blow away most of your bromine. You could try the same at room temperature with GAA and bromine, but I suspect the same problem. perhaps you can put a nonreactive mesh in the reaction vessel to slow down and break up the bubbles as much as possible so it can be done at room temperature.

[Edited on 12-3-08 by UnintentionalChaos]