Difluoroacetic acid

Difluoroacetic acid

Names
IUPAC name 2,2-Difluoroethanoic acid
Other names 2,2-Difluoroacetic acid DFA
Identifiers
Jmol-3D images	Image
SMILES C(C(=O)O)(F)F
Properties
Chemical formula	C2H2F2O2 CHF2COOH
Molar mass	96.033 g/mol
Appearance	Colorless liquid
Odor	Odorless
Density	1.526 g/cm3 (at 25 °C)
Melting point	−1 °C (30 °F; 272 K)
Boiling point	132–134 °C (270–273 °F; 405–407 K)
Solubility in water	Miscible
Solubility	Miscible with alcohols
Acidity (pKa)	1.13
Hazards
Safety data sheet	Sigma-Aldrich
Flash point	78 °C (172.4 °F; 351 K)
Related compounds
Related compounds	Acetic acid Fluoroacetic acid Trifluoroacetic acid
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Difluoroacetic acid is a chemical compound with chemical formula CHF₂COOH.

Properties

Chemical

Difluoroacetic acid reacts with bases to form the corresponding difluoroacetate salts.

Physical

Difluoroacetic acid is a colorless liquid, miscible with water and alcohols.

Availability

DFA is sold by lab suppliers.

Preparation

Can be prepared by refluxing KF with dichloroacetic acid.

Projects

• Make difluoroacetate salts

Handling

Safety

Difluoroacetic acid is toxic, though less so than its monofluoroacetic derivate. Chronic exposure has been linked to nerve and liver damage.

Storage

In closed bottles, with a PTFE seal and a hazardous chemical label.

Disposal

Should be neutralized with a base. The resulting salts should be taken to waste disposal facilities or recycled.

References

Relevant Sciencemadness threads

• Difluoroacetic acid